Piperazine → Ethyl 1,4-diazabicyclo(2.2.2)octane-2-carboxylate
Reaction equation
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[CH:8]([CH2:14]Br)[C:9]([O:11][CH2:12][CH3:13])=[O:10]>>[N:1]12[CH2:6][CH2:5][N:4]([CH2:3][CH2:2]1)[CH2:14][CH:8]2[C:9]([O:11][CH2:12][CH3:13])=[O:10]Participants
3
Procedure
reacting piperazine and ethyl 2,3-dibromopropanoate to form ethyl 1,4-diazabicyclo[2.2.2]octane-2-carboxylate;
Sources & evidence
- ORD record
- ord-7c7adc39bedc4ea9bb4fdca440cf8d46
- Source dataset
- uspto-grants-2000_05
- Patent number
- US06057321
Reaction notes
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