Acetic Anhydride → 3-(6-Fluoroquinol-2-yl-trans-ethenyl)benzaldehyde
Reaction equation
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([F:12])[CH:8]=2)[N:3]=1.[CH:13]1[CH:18]=[C:17]([CH:19]=[O:20])[CH:16]=[C:15]([CH:21]=O)[CH:14]=1.C(OC(=O)C)(=O)C>C1(C)C(C)=CC=CC=1>[F:12][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2](/[CH:1]=[CH:21]/[C:15]1[CH:16]=[C:17]([CH:18]=[CH:13][CH:14]=1)[CH:19]=[O:20])[CH:11]=[CH:10]2Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Using the procedure of Preparation I1, 5.04 g of 2-methyl-6-fluoroquinoline, 4.20 g of isophthaldehyde and 8.86 ml of acetic anhydride in 100 ml of xylene gave 4.40 g of the titled product as a pale yellow solid, m.p. 110°-111° C.