Methyl 3-formylbenzoate → HCID 19102613, compound
Reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])=O.[Cl-].C1([P+](C2C=CC=CC=2)(C2C=CC=CC=2)[CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=2)C=CC=CC=1.C([Li])CCC>O1CCCC1>[N:23]1[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=1/[CH:21]=[CH:1]/[C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[C:6]([O:8][CH3:9])=[O:7]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Using the procedure of Preparation H1, 750 mg of methyl 3-formylbenzoate, 2.14 g of triphenyl 2-pyridylmethyl phosphonium chloride and 2.0 ml of a 2.5M solution of n-butyl lithium in 30 ml of dry tetrahydrofuran gave 496 mg of the titled product.
Sources & evidence
- ORD record
- ord-c6401d457251463eb48286b76f2e344e
- Source dataset
- uspto-grants-1994_06
- Patent number
- US05322847
Reaction notes
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