Hydrochloric Acid → HCID 15670949, compound
Reaction equation
[C:1]([C:3](=[C:9]([C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)[C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[CH2:4][CH2:5][C:6]([OH:8])=[O:7])#[N:2].[OH-:26].[Na+].Cl>C(O)CO>[C:1]([C:3](=[C:9]([C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)[CH2:4][CH2:5][C:6]([OH:8])=[O:7])(=[O:26])[NH2:2]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Two grams of the acid obtained in Example 4 was heated with 10 ml of a 5N aqueous solution of NaOH in 50 ml of ethylene glycol at 150° C. for 12 hours. The product mixture was acidified with hydrochloric acid and extracted with ethyl acetate. The extract was treated with the chromatography of silicagel to obtain 0.5 g of the above intended compound.