Water → N-(cyclobutylmethyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine

HRID 1115064

Reaction equation

HRID 1115064 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][c:7]([C:21]([F:22])([F:23])[F:24])[cH:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[n:10]1.[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[CH:25]1([CH2:29][NH2:30])[CH2:26][CH2:27][CH2:28]1.[OH2:31]>>[c:5]1([NH:30][CH2:29][CH:25]2[CH2:26][CH2:27][CH2:28]2)[n:6][c:7]([C:21]([F:22])([F:23])[F:24])[cH:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[n:10]1

Participants

5

Reactant 4

HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 409746CyclobutylmethylamineHCID 111764432-(Methylsulfonyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidine

Product 1

HCID 9800275N-(cyclobutylmethyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-e8fb37692dc247189f42625fa11ace3b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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