Triethylamine → 1-(2-cyanoethyl)-N-[(3,4-dichlorophenyl)methyl]-4-hydroxy-N-methyl-5-oxo-2H-pyrrole-3-carboxamide

HRID 1121710Notes

Reaction equation

HRID 1121710 reaction equation
[CH2:23]([N:24]([CH2:25][CH3:26])[CH2:27][CH3:28])[CH3:29].[Cl:1][c:2]1[cH:3][c:4]([CH2:9][N:10]([CH3:11])[C:12](=[O:13])[CH:14]=[C:15]2[C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[O:22]2)[cH:5][cH:6][c:7]1[Cl:8].[Cl:30][c:31]1[cH:32][c:33]([CH2:34][N:35]([C:36](=[O:37])[C:38]2=[C:39]([OH:54])[C:40](=[O:53])[N:41]([CH2:43][CH2:44][C:45]([NH:47][CH2:46][CH2:48][C:49]([OH:50])=[O:51])=[O:52])[CH2:42]2)[CH3:55])[cH:56][cH:57][c:58]1[Cl:59]>>[Cl:30][c:31]1[cH:32][c:33]([CH2:34][N:35]([C:36](=[O:37])[C:38]2=[C:39]([OH:54])[C:40](=[O:53])[N:41]([CH2:43][CH2:44][C:45]#[N:47])[CH2:42]2)[CH3:55])[cH:56][cH:57][c:58]1[Cl:59]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 546917263-[3-[3-[(3,4-dichlorophenyl)methyl-methyl-carbamoyl]-4-hydroxy-5-oxo-2H-pyrrol-1-yl]propanoylamino]propanoic acidHCID 69655735N-(3,4-Dichloro-benzyl)-2-(2,2-dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-methyl-acetamide

Product 1

HCID 546982111-(2-cyanoethyl)-N-[(3,4-dichlorophenyl)methyl]-4-hydroxy-N-methyl-5-oxo-2H-pyrrole-3-carboxamide

Sources & evidence

ORD record
ord-b6c8dabf867343b6afb0b707c3b2a649
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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