Hydrochloric Acid → 2-{[6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid ethyl ester

HRID 1121930

Reaction equation

HRID 1121930 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][CH2:17][C:18]34[CH2:19][O:20][CH2:21]4)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[ClH:22].[NH2:23][C:24]([C:25](=[O:26])[O:27][CH2:28][CH3:29])([CH2:30][CH3:31])[CH2:32][CH3:33]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][CH2:17][C:18]34[CH2:19][O:20][CH2:21]4)[cH:8][cH:9][c:10]([C:12](=[O:13])[NH:23][C:24]([C:25](=[O:26])[O:27][CH2:28][CH3:29])([CH2:30][CH3:31])[CH2:32][CH3:33])[n:11]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 437603Ethyl 2-amino-2-ethylbutanoateHCID 710877046-(Cyclopropylmethoxy)-5-(6-oxa-1-azaspiro[3.3]heptan-1-yl)picolinic acid

Product 1

HCID 710878402-{[6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid ethyl ester

Sources & evidence

ORD record
ord-62fdf2acdbac4ff7b0d36e563ed32997
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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