Water → 7-(acetylamino-methyl)-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

HRID 1124963

Reaction equation

[C:28]([CH3:29])(=[O:30])[Cl:31].[C:2]([CH3:3])([CH3:4])([CH3:5])[O:6][C:7](=[O:8])[c:9]1[c:10]([NH2:20])[s:11][c:12]2[c:17]1[CH2:16][CH2:15][O:14][CH:13]2[CH2:18][NH2:19].[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:32][CH2:33][Cl:34].[OH2:1]>>[C:2]([CH3:3])([CH3:4])([CH3:5])[O:6][C:7](=[O:8])[c:9]1[c:10]([NH2:20])[s:11][c:12]2[c:17]1[CH2:16][CH2:15][O:14][CH:13]2[CH2:18][NH:19][C:28]([CH3:29])=[O:30]

Participants

Reactant 5

HCID 962Water

HCID 6344Dichloromethane

HCID 6367Acetyl chloride

HCID 8471Triethylamine

HCID 695860292-amino-7-aminomethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

Product 1

HCID 543731817-(acetylamino-methyl)-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid tert-butyl ester

Sources & evidence

ORD record: ord-8723cb0ced8141e0924b8136ad7b4b33
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Linked notes

Loading…