Tetrahydrofuran → N-{3-[3-(2-{[3-(1,3-Oxazol-5-yl)phenyl]amino}-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

HRID 1126523

Reaction equation

HRID 1126523 reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26](-[c:30]4[cH:31][n:32][cH:33][o:34]4)[cH:27][cH:28][cH:29]3)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1.[s:35]1[c:36]([CH2:40][C:41](=[O:42])[Cl:43])[cH:37][cH:38][cH:39]1>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26](-[c:30]4[cH:31][n:32][cH:33][o:34]4)[cH:27][cH:28][cH:29]3)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1)[C:41]([CH2:40][c:36]1[s:35][cH:39][cH:38][cH:37]1)=[O:42]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 1623622-Thiopheneacetyl chlorideHCID 577371674-[2-(3-Aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-[3-(1,3-oxazol-5-yl)phenyl]-2-pyrimidinamine

Product 1

HCID 57737194N-{3-[3-(2-{[3-(1,3-Oxazol-5-yl)phenyl]amino}-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

Sources & evidence

ORD record
ord-caa003737cff48a7bce83b0534dd6c24
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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