Bicarbonate Ion → 2-Chloro-5-(trifluoromethyl)nicotinonitrile

HRID 1128617

Reaction equation

HRID 1128617 reaction equation
[C:16](#[N:17])[c:18]1[c:19]([OH:28])[n:20][cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1.[C:29](=[O:30])([OH:31])[O-:32].[Na+:33].[OH2:34].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5].[cH:6]1[cH:7][c:8]2[c:9]([n:10][cH:11][cH:12][cH:13]2)[cH:14][cH:15]1>>[Cl:3][c:19]1[c:18]([C:16]#[N:17])[cH:23][c:22]([C:24]([F:25])([F:26])[F:27])[cH:21][n:20]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 7047QuinolineHCID 24813Phosphorus oxychlorideHCID 148370202-Oxo-5-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile

Product 1

HCID 200715992-Chloro-5-(trifluoromethyl)nicotinonitrile

Sources & evidence

ORD record
ord-8ef2874b6a4d4673afd43b8a4c82071b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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