Sodium Ion → 3-(3-Fluoro-5-chloro-2-pyridyl)-5-bromo-1-methyl-[1H]-pyrazole

Reaction equation

[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[Cl:16][CH2:17][C:18]([Cl:19])([Cl:20])[Cl:21].[F:1][c:2]1[c:3](-[c:9]2[n:10][n:11]([CH3:15])[c:12]([OH:14])[cH:13]2)[n:4][cH:5][c:6]([Cl:8])[cH:7]1.[Na+:28].[OH-:27].[P:22]([Br:23])([Br:24])([Br:25])=[O:26]>>[F:1][c:2]1[c:3](-[c:9]2[n:10][n:11]([CH3:15])[c:12]([Br:24])[cH:13]2)[n:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 3283Diethyl Ether

HCID 124181,1,1,2-Tetrachloroethane

HCID 24613Phosphorus oxybromide

HCID 178481771HCID 178481771, compound

Product 1

HCID 217121223-(3-Fluoro-5-chloro-2-pyridyl)-5-bromo-1-methyl-[1H]-pyrazole

Sources & evidence

ORD record: ord-0ad0eb33cae440e0945433e4197a18b4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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