Sodium Ion → 3-bromo-5-nito-1-(difluoromethoxy)benzene

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([OH:11])[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[Cl:14][C:15]([C:16]([O-:17])=[O:18])([F:19])[F:20].[Na+:13].[Na+:21].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[OH-:12]>>[Br:1][c:2]1[cH:3][c:4]([O:11][CH:15]([F:19])[F:20])[cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

Reactant 5

HCID 923Sodium Ion2×

HCID 961Hydroxide

HCID 6228Dimethylformamide

HCID 37630462-Chloro-2,2-difluoroacetate

HCID 104889843-Bromo-5-nitrophenol

Product 1

HCID 670535603-bromo-5-nito-1-(difluoromethoxy)benzene

Sources & evidence

ORD record: ord-07d6dc1d31ec4fb38c02223305a24d3a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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