Methyl 4-Iodo-3-methylbenzoate → Methyl 3-methyl-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthryl)benzoate

HRID 1138

Reaction equation

HRID 1138 reaction equation
[CH3:1][C:2]1([CH3:21])[CH2:15][CH2:14][C:13]([CH3:17])([CH3:16])[C:12]2[CH:11]=[C:10]3[C:5]([CH:6]=[CH:7][C:8](B(O)O)=[CH:9]3)=[CH:4][C:3]1=2.[CH3:22][C:23]1[CH:24]=[C:25]([CH:30]=[CH:31][C:32]=1I)[C:26]([O:28][CH3:29])=[O:27]>>[CH3:22][C:23]1[CH:24]=[C:25]([CH:30]=[CH:31][C:32]=1[C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][C:12]3[C:13]([CH3:17])([CH3:16])[CH2:14][CH2:15][C:2]([CH3:21])([CH3:1])[C:3]=3[CH:4]=2)[CH:9]=1)[C:26]([O:28][CH3:29])=[O:27]

Participants

3

Reactant 2

HCID 231757Methyl 4-Iodo-3-methylbenzoateHCID 196946765,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthrylboronic acid

Product 1

HCID 19694687Methyl 3-methyl-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthryl)benzoateYield 53%

Procedure

Following the basic procedure of Example 7(f), by reacting 2.8 g (10 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthrylboronic acid with 1.84 g (6.7 mmol) of methyl 3-methyl-4-iodobenzoate, 1.37 g (53%) of methyl 3-methyl-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthryl)benzoate was obtained in the form of a yellow oil.

Sources & evidence

ORD record
ord-7949d567ab7542a8990b7bcf17a467de
Source dataset
uspto-grants-1998_03
Patent number
US05723499

Linked notes

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