Water → N-(p-toluenesulfonyl)-3-(aminoethyl)-4-(bromomethyl)-3-pyrroline

Reaction equation

[Al+3:22].[CH2:28]([O:29][CH2:30][CH3:31])[CH3:32].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[OH2:27].[c:1]1([CH3:20])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH2:11][C:12]([CH2:18][Br:19])=[C:13]([CH2:15][C:16]#[N:17])[CH2:14]2)[cH:5][cH:6]1>>[c:1]1([CH3:20])[cH:2][cH:3][c:4]([S:7](=[O:8])(=[O:9])[N:10]2[CH2:11][C:12]([CH2:18][Br:19])=[C:13]([CH2:15][CH2:16][NH2:17])[CH2:14]2)[cH:5][cH:6]1

Participants

Reactant 6

HCID 962Water

HCID 3283Diethyl Ether

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 19908246N-(p-toluenesulfonyl)-3-(bromomethyl)4-(cyanomethyl)-3-pyrroline

Product 1

HCID 54170899N-(p-toluenesulfonyl)-3-(aminoethyl)-4-(bromomethyl)-3-pyrroline

Sources & evidence

ORD record: ord-321bfc4cf6744b0e91af015a09c8327f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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