Water → 5-(5-Bromoacetyl-2-n-propoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

HRID 1147647

Reaction equation

HRID 1147647 reaction equation
[Br:29][CH2:30][C:31](=[O:32])[Cl:33].[CH3:5][n:6]1[n:7][c:8]([CH2:26][CH2:27][CH3:28])[c:9]2[n:10][c:11](-[c:16]3[c:17]([O:22][CH2:23][CH2:24][CH3:25])[cH:18][cH:19][cH:20][cH:21]3)[nH:12][c:13](=[O:15])[c:14]12.[Cl:1][Al:2]([Cl:3])[Cl:4].[Cl:35][CH2:36][Cl:37].[OH2:34]>>[CH3:5][n:6]1[n:7][c:8]([CH2:26][CH2:27][CH3:28])[c:9]2[n:10][c:11](-[c:16]3[c:17]([O:22][CH2:23][CH2:24][CH3:25])[cH:18][cH:19][c:20]([C:31]([CH2:30][Br:29])=[O:32])[cH:21]3)[nH:12][c:13](=[O:15])[c:14]12

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 24012Aluminum ChlorideHCID 89602Bromoacetyl chlorideHCID 1357385471-Methyl-5-(2-propoxyphenyl)-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

Product 1

HCID 1361616085-(5-Bromoacetyl-2-n-propoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one

Sources & evidence

ORD record
ord-42d35b4dfff540c688bf6e7c1c2350af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

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