Pyridine → Tert-butyl 2-cyano-4-hydroxy-pyrrolidine-1-carboxylate
Reaction equation
[C:1]([NH2:2])(=[O:3])[CH:4]1[N:5]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:6][CH:7]([OH:9])[CH2:8]1.[F:17][C:18]([F:19])([F:20])[C:21]([O:22][C:23](=[O:24])[C:25]([F:26])([F:27])[F:28])=[O:29].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[C:1](#[N:2])[CH:4]1[N:5]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:6][CH:7]([OH:9])[CH2:8]1Participants
4
Sources & evidence
- ORD record
- ord-38a2a8a5bae4436ea8fe935f3585fc5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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