Water → 4-[(4-Bromo-3-phenyl-1,2-thiazol-5-yl)oxy]-5-chloro-2-methylaniline

Reaction equation

[Br:1][c:2]1[c:3](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:4][s:5][c:6]1[Cl:7].[C:23]([O-:24])(=[O:25])[O-:26].[CH3:29][N:30]([CH3:31])[CH:32]=[O:33].[Cs+:27].[Cs+:28].[NH2:14][c:15]1[cH:16][c:17]([Cl:22])[cH:18][cH:19][c:20]1[CH3:21].[OH2:34]>>[Br:1][c:2]1[c:3](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:4][s:5][c:6]1[O:24][c:18]1[c:17]([Cl:22])[cH:16][c:15]([NH2:14])[c:20]([CH3:21])[cH:19]1

Participants

Reactant 6

HCID 962Water

HCID 6228Dimethylformamide

HCID 72605-Chloro-2-methylaniline

HCID 19660Carbonate Ion

HCID 104967Cesium cation2×

HCID 58283713HCID 58283713, compound

Product 1

HCID 582837174-[(4-Bromo-3-phenyl-1,2-thiazol-5-yl)oxy]-5-chloro-2-methylaniline

Sources & evidence

ORD record: ord-7b1ff99ccc154fbd9f31cefc0b412ee0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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