Bicarbonate Ion → 2-Amino-4-[4-(2-methoxyethoxy)phenyl]-6-[(2-amino-1,3-thiazol-4-yl)methylsulphanyl]pyridine-3,5-dicarbonitrile

HRID 1151636

Reaction equation

HRID 1151636 reaction equation
[C:24](=[O:25])([OH:26])[O-:27].[Cl:29][CH2:30][c:31]1[n:32][c:33]([NH2:36])[s:34][cH:35]1.[NH2:1][c:2]1[n:3][c:4]([SH:23])[c:5]([C:21]#[N:22])[c:6](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][O:19][CH3:20])[cH:14][cH:15]2)[c:7]1[C:8]#[N:9].[Na+:28].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42].[OH2:37]>>[NH2:1][c:2]1[n:3][c:4]([S:23][CH2:30][c:31]2[n:32][c:33]([NH2:36])[s:34][cH:35]2)[c:5]([C:21]#[N:22])[c:6](-[c:10]2[cH:11][cH:12][c:13]([O:16][CH2:17][CH2:18][O:19][CH3:20])[cH:14][cH:15]2)[c:7]1[C:8]#[N:9]

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 732294-Chloromethylthiazol-2-ylamineHCID 178496105HCID 178496105, compound

Product 1

HCID 219490822-Amino-4-[4-(2-methoxyethoxy)phenyl]-6-[(2-amino-1,3-thiazol-4-yl)methylsulphanyl]pyridine-3,5-dicarbonitrile

Sources & evidence

ORD record
ord-8cd08e9f69764e03a0add0080e92855f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Linked notes

Loading…