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Tetrahydrofuran → 3,6-Diethoxy-2-{2-[8-(2-methoxyethoxy)naphthalen-2-ylmethyl]-3-methylbutyl}-2,5-dihydropyrazine

HRID 1152700
Notes
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Reaction equation

HRID 1152700 reaction equation
[Br:18][CH2:19][CH:20]([CH2:21][c:22]1[cH:23][cH:24][c:25]2[cH:26][cH:27][cH:28][c:29]([O:32][CH2:33][CH2:34][O:35][CH3:36])[c:30]2[cH:31]1)[CH:37]([CH3:38])[CH3:39].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:6]([CH3:7])[O:8][C:9]1=[N:14][CH2:13][C:12]([O:15][CH2:16][CH3:17])=[N:11][CH2:10]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[CH2:6]([CH3:7])[O:8][C:9]1=[N:14][CH2:13][C:12]([O:15][CH2:16][CH3:17])=[N:11][CH:10]1[CH2:19][CH:20]([CH2:21][c:22]1[cH:23][cH:24][c:25]2[cH:26][cH:27][cH:28][c:29]([O:32][CH2:33][CH2:34][O:35][CH3:36])[c:30]2[cH:31]1)[CH:37]([CH3:38])[CH3:39]
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 111267023,6-Diethoxy-2,5-dihydropyrazineHCID 668884037-(2-Bromomethyl-3-methylbutyl)-1-(2-methoxyethoxy)naphthaleneHCID 178418339Butyllithium

Product 1

HCID 668877873,6-Diethoxy-2-{2-[8-(2-methoxyethoxy)naphthalen-2-ylmethyl]-3-methylbutyl}-2,5-dihydropyrazine

Sources & evidence

ORD record
ord-21866c6ed7054f98a0a540da0d91118b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes