Iodoethane → HCID 12813182, compound

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12](=[O:13])[C:11]([C:14]3[CH:15]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:17]=[CH:18][CH:19]=3)=[CH:10][NH:9]2)[CH:5]=[CH:6][CH:7]=1.[CH2:24](I)[CH3:25]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12](=[O:13])[C:11]([C:14]3[CH:15]=[C:16]([C:20]([F:21])([F:22])[F:23])[CH:17]=[CH:18][CH:19]=3)=[CH:10][N:9]2[CH2:24][CH3:25])[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 6340Iodoethane

HCID 12813178HCID 12813178, compound

Product 1

HCID 12813182HCID 12813182, compound

Procedure

A 2.6 gram portion of 1-(3-chlorophenyl)-4-(α,α,α-trifluoro-3-tolyl)-3-pyrazolin-5-one, prepared in Example 3, was alkylated with ethyl iodide to produce 0.25 grams of the desired product, an oily liquid.

Sources & evidence

ORD record: ord-542424f6ed21497cbfb02441f7e16ed4
Source dataset: uspto-grants-1981_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04299614

Reaction notes

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