Bicarbonate Ion → N-cyclohexyl-5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-amine
Reaction equation
[CH3:19][N:20]1[CH2:21][CH2:22][N:23]([CH3:24])[C:25]1=[O:26].[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[F:8])[nH:9][cH:10][cH:11]2.[NH2:12][CH:13]1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1.[Na+:33].[OH:34][C:35](=[O:36])[O-:37]>>[c:2]1([NH:12][CH:13]2[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]2)[c:3]2[c:4]([n:5][cH:6][c:7]1[F:8])[nH:9][cH:10][cH:11]2Participants
7
Sources & evidence
- ORD record
- ord-e94407dab84b489b85dbbb1e36ef7bc7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…