P-Toluic Acid → 4-Methylbenzoyl Chloride
Reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:13])=[O:7])=[CH:4][CH:3]=1Participants
3
Procedure
4-Methylbenzoyl chloride was prepared in a conventional manner from 4-methylbenzoic acid and thionyl chloride and after excess thionyl chloride was distilled off, was used as the crude product in the side chain chlorination.
Workup
- distillationafter excess thionyl chloride was distilled off
Sources & evidence
- ORD record
- ord-4c3ca7fee7ca4cb68a75ae1c5be3919e
- Source dataset
- uspto-grants-1998_03
- Patent number
- US05723613
Reaction notes
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