D-Xylulose → aldehydo-D-Xylose

HRID 1161631

Reaction equation

HRID 1161631 reaction equation
[CH2:1]([OH:10])[C@@H:2]([C@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3].[OH:11][CH2:12][C:13]([C@H:15]([C@@H:17]([CH2:19][OH:20])[OH:18])[OH:16])=[O:14]>>[CH2:1]([OH:10])[C@@H:2]([C@H:4]([C@@H:6]([CH2:8][OH:9])[OH:7])[OH:5])[OH:3].[O:11]=[CH:12][C@@H:13]([C@H:15]([C@@H:17]([CH2:19][OH:20])[OH:18])[OH:16])[OH:14]

Participants

4

Reactant 2

HCID 5289590D-XyluloseHCID 178418489HCID 178418489, compound3×

Product 2

HCID 644160aldehydo-D-XyloseHCID 178418489HCID 178418489, compound

Procedure

Paying attention to the fact that xylitol produced in Candida sp strains is reduced by its conversion to xylulose by xylitol dehydrogenase, the present inventors have developed xylitol dehydrogenase-inactivated Candida tropicalis mutant, in which xylitol produced from xylose can no longer be used for cell growth, and thus xylose can be bioconverted to xylitol with a theoretical yield of 100% (Ko, B. S. et. al., Appl. Environ. Microbiol. 72:4207-4213, 2006). Thus, the present inventors filed an application for the protection of an invention relating to a method of producing xylitol in high yield using a xylitol-producing strain, in which the expression of xylitol dehydrogenase is inhibited (Korean Patent Application No. 10-2005-0079751, filed on Aug. 30, 2005).

Workup

  1. customproduced in Candida sp strains

Sources & evidence

ORD record
ord-7efaf3d8aede43c6ad7f9fb6317b3920
Source dataset
uspto-grants-2010_10
Patent number
US07820414B2

Linked notes

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