Dimethylformamide → 2,5-dimethylfuran-3-sulfonyl Chloride

HRID 1166919

Reaction equation

HRID 1166919 reaction equation
CN(C=O)C.[S:6]([Cl:10])(Cl)(=[O:8])=[O:7].[CH3:11][C:12]1[O:13][C:14]([CH3:17])=[CH:15][CH:16]=1>>[CH3:11][C:12]1[O:13][C:14]([CH3:17])=[CH:15][C:16]=1[S:6]([Cl:10])(=[O:8])=[O:7]

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 122662,5-DimethylfuranHCID 24648Sulfuryl chloride

Product 1

HCID 27950242,5-dimethylfuran-3-sulfonyl Chloride

Procedure

2,5-dimethyl-furan-3-sulfonylchloride was prepared by the method of Example 40B with DMF (28 mmoles, 2.2 ml), sulfurylchloride (24 mmoles, 1.9 ml) and 2,5-dimethyl-furan (14 mmoles, 1.5 ml). Flash chromatography (5% ethyl acetate/hexanes) provided 0.61 g (22%) of a yellow liquid.

Sources & evidence

ORD record
ord-1b0a7ec0a537403db2f594cce2e021e6
Source dataset
uspto-grants-2003_09
Patent number
US06613804B2

Linked notes

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