Diglyme → HCID 178418794, compound

HRID 1167971

Reaction equation

HRID 1167971 reaction equation
[CH2:1]([O:3][C:4](=[O:11])[C:5]([N:7](C=O)[NH2:8])=[NH:6])[CH3:2].[CH3:12]OCCOCCOC>>[CH2:1]([O:3][C:4]([C:5]1[N:6]=[CH:12][NH:8][N:7]=1)=[O:11])[CH3:2]

Participants

3

Reactant 2

HCID 8150DiglymeHCID 86590617(N-Formylhydrazino)-imino acetic acid ethyl ester

Product 1

HCID 178418794HCID 178418794, compoundYield 85%

Procedure

A suspension of (N-Formylhydrazino)-imino acetic acid ethyl ester (9.62 g, 60.4 mmol) in diglyme (40 ml) was refluxed for 30 minutes. After cooling, the precipitated crystal was collected by filteration and washed with hexane to give 1H-1,2,4-triazol-3-carboxylic acid ethyl ester (7.28 g) Yield: 85%.

Workup

  1. temperaturewas refluxed for 30 minutes
  2. temperatureAfter cooling
  3. customthe precipitated crystal was collected by filteration
  4. washwashed with hexane

Sources & evidence

ORD record
ord-3e8304c1d3bd416888d2af186eeafa91
Source dataset
uspto-grants-2003_09
Patent number
US06620841B1

Linked notes

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