N,N-Dimethylglycine → Methyl 3-(6-aminopyridin-3-yloxy)benzoate

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1.[C:27](=[O:28])([O-:29])[O-:30].[CH3:20][N:21]([CH2:22][C:23](=[O:24])[OH:25])[CH3:26].[Cs+:31].[Cs+:32].[Cu:39][I:40].[O:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1.[OH:9][c:10]1[cH:11][c:12]([C:13](=[O:14])[O:15][CH3:16])[cH:17][cH:18][cH:19]1>>[c:2]1([O:9][c:10]2[cH:11][c:12]([C:13](=[O:14])[O:15][CH3:16])[cH:17][cH:18][cH:19]2)[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1

Participants

Reactant 7

HCID 673N,N-Dimethylglycine

HCID 19660Carbonate Ion

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 312751,4-Dioxane

HCID 706222-Amino-5-bromopyridine

HCID 88068Methyl 3-Hydroxybenzoate

HCID 104967Cesium cation2×

Product 1

Sources & evidence

ORD record: ord-01eda7c11b9948f4a3389293ed16da88
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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