4-(Bromoacetyl)benzonitrile → (R)-4-[2-(1-Methyl-2,2,2-trifluoroethylamino)-thiazol-4-yl]-benzonitrile
Reaction equation
[C:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7](=O)[CH2:8]Br)=[CH:5][CH:4]=1)#[N:2].[CH3:13][C@@H:14]([NH:19][C:20]([NH2:22])=[S:21])[C:15]([F:18])([F:17])[F:16].C(=O)(O)[O-].[Na+]>C(O)C>[CH3:13][C@@H:14]([NH:19][C:20]1[S:21][CH:8]=[C:7]([C:6]2[CH:11]=[CH:12][C:3]([C:1]#[N:2])=[CH:4][CH:5]=2)[N:22]=1)[C:15]([F:18])([F:17])[F:16]Participants
5
