Ethyl Acrylate → Ethyl 3-{N-[3-(pyrid-4-yl)propyl]-N-methyl-amino}-propionate
Reaction equation
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[CH:2]=[CH2:3].[N:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][NH:17][CH3:18])=[CH:10][CH:9]=1>C(OCC)C>[N:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][N:17]([CH2:3][CH2:2][C:1]([O:5][CH2:6][CH3:7])=[O:4])[CH3:18])=[CH:10][CH:9]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
15.1 g of ethyl acrylate are added portionwise to a solution of 22.5 g (0,15 Mol) of N-[3-(pyrid-4-yl)propyl]-N-methyl-amine in 50 ml of diethyl ether. The clear solution formed is allowed to stand overnight. The solvent is evaporated off. Ethyl 3-{N-[3-(pyrid-4-yl)propyl]-N-methyl-amino}-propionate is thus obtained as an oil.
Workup
- customThe clear solution formed
- customThe solvent is evaporated off
Sources & evidence
- ORD record
- ord-bc7e9802b4cd4bc193de1ba57f526a56
- Source dataset
- uspto-grants-1992_05
- Patent number
- US05110807
Reaction notes
Loading…