Pyrilamine hydrochloride → Pyrilamine

HRID 1197477

Reaction equation

HRID 1197477 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][N:6]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][N:21]=1)[CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH3:15])=[CH:12][CH:13]=1)[CH3:3].Cl>O>[CH3:1][N:2]([CH2:4][CH2:5][N:6]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][N:21]=1)[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1)[CH3:3]

Participants

3

Reactant 1

HCID 80139Pyrilamine hydrochloride2×

Product 1

HCID 4992PyrilamineYield 99.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A second solution of antihistamine was prepared by dissolving 1.52 grams of the pyrilamine HCl in 60 ml of purified water. The molecular weight of the pyrilamine hydrochloride is 321.9 which resulted in an aqueous solution of 4.7×10-3 moles of pyrilamine. The pH of the solution was adjusted to 7.4 with Na2HPO4 ·7H2O.

Workup

  1. customA second solution of antihistamine was prepared

Sources & evidence

ORD record
ord-7a27fe42fd3640e187b42e3d8cb4884e
Source dataset
uspto-grants-1994_01
Patent number
US05276044

Linked notes

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