Sodium ion → N-(5-(4-chloro-3-methylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotin-amide

HRID 1201016

Reaction equation

HRID 1201016 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:14][C:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)=[O:22])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13].[CH3:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:30][c:31]1[c:32]([CH3:40])[cH:33][c:34]([B:37]([OH:38])[OH:39])[cH:35][cH:36]1.[Na+:41].[Na+:42].[O-:43][C:44](=[O:45])[O-:46]>>[c:2]1(-[c:34]2[cH:33][c:32]([CH3:40])[c:31]([Cl:30])[cH:36][cH:35]2)[cH:3][c:4]([NH:14][C:15]([c:16]2[cH:17][n:18][cH:19][cH:20][cH:21]2)=[O:22])[cH:5][n:6][c:7]1[O:8][CH2:9][C:10]([F:11])([F:12])[F:13]

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 1140TolueneHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 3786632(4-Chloro-3-methylphenyl)boronic acidHCID 67280716N-(5-bromo-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotinamide

Product 1

HCID 56961331N-(5-(4-chloro-3-methylphenyl)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)nicotin-amide

Sources & evidence

ORD record
ord-3808a07d84e54a75a83e84c11bc94c95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

Loading…