Sodium ion → 4-(1-but-2-enoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1H-quinoline

HRID 1201557

Reaction equation

HRID 1201557 reaction equation
[Br:74][CH2:75][CH:76]=[CH:77][CH2:78][CH3:79].[C:1]([O:2][C:3]([N:4]1[c:5]2[c:6]([cH:7][c:8](-[c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[O:15][CH3:16])[cH:17][cH:18]2)[C:19]([CH:20]([OH:21])[CH3:22])=[CH:23][C:24]1([CH3:25])[CH3:26])=[O:27])([CH3:28])([CH3:29])[CH3:30].[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[CH3:31][O:32][c:33]1[c:34](-[c:39]2[cH:40][c:41]3[c:46]([cH:47][cH:48]2)[NH:45][C:44]([CH3:49])([CH3:50])[CH:43]=[C:42]3[CH:51]([CH3:52])[O:53][CH2:54][CH:55]=[CH:56][CH2:57][CH3:58])[cH:35][cH:36][cH:37][cH:38]1.[CH3:59][Si:60]([N-:61][Si:62]([CH3:63])([CH3:64])[CH3:65])([CH3:66])[CH3:67].[Na+:68]>>[CH3:31][O:32][c:33]1[c:34](-[c:39]2[cH:40][c:41]3[c:46]([cH:47][cH:48]2)[NH:45][C:44]([CH3:49])([CH3:50])[CH:43]=[C:42]3[CH:51]([CH3:52])[O:53][CH2:54][CH:55]=[CH:56][CH3:57])[cH:35][cH:36][cH:37][cH:38]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 1407151-Bromo-pent-2-eneHCID 3280088Npc316347HCID 207603324-(1-hydroxyethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-2H-quinoline-1-carboxylic acid tert-butyl esterHCID 69152456HCID 69152456, compound

Product 1

HCID 691533384-(1-but-2-enoxyethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1H-quinoline

Sources & evidence

ORD record
ord-542ef013d3df4a42ac67d5854bd0669b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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