Trifluoroacetic acid → 6-((trans)-4-aminocyclohexylamino)-8-(cyclopropylamino)-N-(2-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

HRID 1201734

Reaction equation

HRID 1201734 reaction equation
[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47].[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[cH:10][c:11]([N:28]([CH2:29][c:30]3[cH:31][cH:32][c:33]([O:34][CH3:35])[cH:36][cH:37]3)[CH:38]3[CH2:39][CH2:40]3)[c:12]3[n:13]([n:14]2)[c:15]([C:18](=[O:19])[NH:20][c:21]2[cH:22][c:23]([F:27])[n:24][cH:25][cH:26]2)[cH:16][n:17]3)[CH2:6][CH2:7]1>>[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[cH:10][c:11]([NH:28][CH:38]3[CH2:39][CH2:40]3)[c:12]3[n:13]([n:14]2)[c:15]([C:18](=[O:19])[NH:20][c:21]2[cH:22][c:23]([F:27])[n:24][cH:25][cH:26]2)[cH:16][n:17]3)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 596246366-((trans)-4-aminocyclohexylamino)-8-(cyclopropyl(4-methoxybenzyl)amino)-N-(2-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

Product 1

HCID 596248256-((trans)-4-aminocyclohexylamino)-8-(cyclopropylamino)-N-(2-fluoropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

Sources & evidence

ORD record
ord-b8d9d9bfa84b4f47a154015bb414bd57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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