Sodium Ion → (3-Bromo-5-methyl-phenyl)-(5-isopropyl-2,6-dimethoxy-pyrimidin-4-yl)-methanone

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([CH:9]([C:10]#[N:11])[c:12]2[n:13][c:14]([O:23][CH3:24])[n:15][c:16]([O:21][CH3:22])[c:17]2[CH:18]([CH3:19])[CH3:20])[cH:5][c:6]([CH3:8])[cH:7]1.[H-:25].[Na+:26].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[Br:1][c:2]1[cH:3][c:4]([C:9]([c:12]2[n:13][c:14]([O:23][CH3:24])[n:15][c:16]([O:21][CH3:22])[c:17]2[CH:18]([CH3:19])[CH3:20])=[O:27])[cH:5][c:6]([CH3:8])[cH:7]1

Participants

Reactant 4

HCID 923Sodium Ion

HCID 6228Dimethylformamide

HCID 166653Hydride

HCID 596868362-(3-Bromo-5-methylphenyl)-2-(5-isopropyl-2,6-dimethoxypyrimidin-4-YL)acetonitrile

Product 1

HCID 59686860(3-Bromo-5-methyl-phenyl)-(5-isopropyl-2,6-dimethoxy-pyrimidin-4-yl)-methanone

Sources & evidence

ORD record: ord-8bacc4392cbb47afb13f29b6619bae6f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…