Phosphorus oxychloride → 7-Chloro-5-cyclopropyl-1,3-dimethyl-pyrazolo[4,3-d]pyrimidine

Reaction equation

[CH:1]1([c:4]2[n:5][c:6]([OH:15])[c:7]3[c:8]([n:9]2)[c:10]([CH3:14])[n:11][n:12]3[CH3:13])[CH2:2][CH2:3]1.[Cl:16][P:17]([Cl:18])([Cl:19])([Cl:20])[Cl:21].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[CH:1]1([c:4]2[n:5][c:6]([Cl:16])[c:7]3[c:8]([n:9]2)[c:10]([CH3:14])[n:11][n:12]3[CH3:13])[CH2:2][CH2:3]1

Participants

Reactant 3

HCID 24813Phosphorus oxychloride

HCID 24819Phosphorus pentachloride

HCID 178433983HCID 178433983, compound

Product 1

HCID 133384087-Chloro-5-cyclopropyl-1,3-dimethyl-pyrazolo[4,3-d]pyrimidine

Sources & evidence

ORD record: ord-e73098ef438d43dbae0c11bf5a38001e
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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