Pyridine → N-(3-chloro-4-methoxyphenylcarbonyl)-4-[bis(4-trifluoromethoxyphenyl)hydroxymethyl]piperidine
Reaction equation
[Cl:37][c:38]1[cH:39][c:40]([C:41](=[O:42])[Cl:43])[cH:44][cH:45][c:46]1[O:47][CH3:48].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([C:10]([CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)([OH:17])[c:18]2[cH:19][cH:20][c:21]([O:24][C:25]([F:26])([F:27])[F:28])[cH:22][cH:23]2)[cH:8][cH:9]1)([F:29])[F:30].[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([C:10]([CH:11]2[CH2:12][CH2:13][N:14]([C:41]([c:40]3[cH:39][c:38]([Cl:37])[c:46]([O:47][CH3:48])[cH:45][cH:44]3)=[O:42])[CH2:15][CH2:16]2)([OH:17])[c:18]2[cH:19][cH:20][c:21]([O:24][C:25]([F:26])([F:27])[F:28])[cH:22][cH:23]2)[cH:8][cH:9]1)([F:29])[F:30]Participants
5
Sources & evidence
- ORD record
- ord-400b4d9868da4f948e84f3385beda8a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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