Hydrochloric Acid → 2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic acid

Reaction equation

[CH3:26][OH:27].[ClH:25].[Na+:24].[O:1]=[C:2]1[NH:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[CH2:11][c:12]1[c:13]([n:14][cH:15][c:16]([C:18](=[O:19])[O:20][CH3:21])[cH:17]1)[CH2:22]2.[OH-:23]>>[O:1]=[C:2]1[NH:3][c:4]2[n:5][cH:6][cH:7][cH:8][c:9]2[C:10]12[CH2:11][c:12]1[c:13]([n:14][cH:15][c:16]([C:18](=[O:19])[OH:20])[cH:17]1)[CH2:22]2

Participants

Reactant 5

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 77603036methyl 2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-carboxylate

Product 1

HCID 775480982'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic acid

Sources & evidence

ORD record: ord-20927d0daf3446da8b67762d06fc26b4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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