2-Fluoropyridine → 5-nitro-N4-{[trans-4-(pyridin-2-ylamino)cyclohexyl]methyl}-N2-[2-(trifluoromethoxy)benzyl]pyrimidine-2,4-diamine
Reaction equation
[F:32][c:33]1[n:34][cH:35][cH:36][cH:37][cH:38]1.[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][NH:9][c:10]2[n:11][c:12]([NH:19][CH2:20][c:21]3[c:22]([O:27][C:28]([F:29])([F:30])[F:31])[cH:23][cH:24][cH:25][cH:26]3)[n:13][cH:14][c:15]2[N+:16](=[O:17])[O-:18])[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][NH:9][c:10]2[n:11][c:12]([NH:19][CH2:20][c:21]3[c:22]([O:27][C:28]([F:29])([F:30])[F:31])[cH:23][cH:24][cH:25][cH:26]3)[n:13][cH:14][c:15]2[N+:16](=[O:17])[O-:18])[CH2:6][CH2:7]1)[c:33]1[n:34][cH:35][cH:36][cH:37][cH:38]1Participants
3
Sources & evidence
- ORD record
- ord-0a0839f857234ac786939fa9fc215c8f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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