Acetic Acid → Ethyl 6-(4-((5-(furo[3,2-c]pyridin-2-yl)-[1,2,4]-oxadiazol-3-yl)methyl)piperidin-1-yl)nicotinate

HRID 1211047

Reaction equation

HRID 1211047 reaction equation
[C:45]([OH:46])(=[O:47])[CH3:48].[CH2:34]1[CH2:35][CH2:36][C:37]2=[N:42][CH2:41][CH2:40][CH2:39][N:38]2[CH2:43][CH2:44]1.[CH3:49][S:50]([CH3:51])=[O:52].[Cl:22][c:23]1[n:24][cH:25][c:26]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:32][cH:33]1.[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][c:8]2[n:9][o:10][c:11](-[c:13]3[cH:14][c:15]4[cH:16][n:17][cH:18][cH:19][c:20]4[o:21]3)[n:12]2)[CH2:5][CH2:6]1>>[N:1]1([c:23]2[n:24][cH:25][c:26]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:32][cH:33]2)[CH2:2][CH2:3][CH:4]([CH2:7][c:8]2[n:9][o:10][c:11](-[c:13]3[cH:14][c:15]4[cH:16][n:17][cH:18][cH:19][c:20]4[o:21]3)[n:12]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 679Dimethyl SulfoxideHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 2799611Ethyl 6-chloronicotinateHCID 116305842-(3-Piperidin-4-ylmethyl-[1,2,4]oxadiazol-5-yl)furo[3,2-c]pyridine

Product 1

HCID 57659479Ethyl 6-(4-((5-(furo[3,2-c]pyridin-2-yl)-[1,2,4]-oxadiazol-3-yl)methyl)piperidin-1-yl)nicotinate

Sources & evidence

ORD record
ord-57c5db7e083c4b2fad66bb2350aa848f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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