Dichloromethane → 6-chloro-4'-[5-chloro-2-(4-piperidinyloxy)-phenyl]-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([CH:22]3[CH2:23][C:24](=[O:46])[NH:25][CH:26]([c:38]4[c:39]([CH3:45])[cH:40][cH:41][c:42]([F:44])[cH:43]4)[C:27]34[C:28](=[O:37])[NH:29][c:30]3[cH:31][c:32]([Cl:36])[cH:33][cH:34][c:35]34)[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:54][CH2:55][Cl:56].[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53]>>[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([CH:22]3[CH2:23][C:24](=[O:46])[NH:25][CH:26]([c:38]4[c:39]([CH3:45])[cH:40][cH:41][c:42]([F:44])[cH:43]4)[C:27]34[C:28](=[O:37])[NH:29][c:30]3[cH:31][c:32]([Cl:36])[cH:33][cH:34][c:35]34)[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
4
