Acetonitrile → Ethyl 6-difluoromethoxymethylpyridine-2-carboxylate

HRID 1215628

Reaction equation

HRID 1215628 reaction equation
[CH3:24][C:25]#[N:26].[Cu:27][I:28].[F:1][C:2]([S:3]([F:4])(=[O:5])=[O:6])([C:7]([OH:8])=[O:9])[F:10].[OH:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][c:17]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:18]1>>[F:1][CH:2]([F:10])[O:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][c:17]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[n:18]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27375162,2-Difluoro-2-(fluorosulfonyl)acetic acidHCID 109211412-Pyridinecarboxylic acid, 6-(hydroxymethyl)-, ethyl ester

Product 1

HCID 66718372Ethyl 6-difluoromethoxymethylpyridine-2-carboxylate

Sources & evidence

ORD record
ord-b9160880ab924bfea1385d1818dea1b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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