Ethyl Acetate → 3-(2-Phenylamino-4-cyclopropylmethylamino-pyrimidin-5-yl)-2-(4-methoxy-phenyl)-propionic acid methyl ester

HRID 1216381

Reaction equation

HRID 1216381 reaction equation
[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[c:7]([Cl:19])[n:8][c:9]([NH:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[n:10][cH:11]1)[c:20]1[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]1)=[O:28].[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[CH:29]1([CH2:32][NH2:33])[CH2:30][CH2:31]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[c:7]([NH:33][CH2:32][CH:29]2[CH2:30][CH2:31]2)[n:8][c:9]([NH:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[n:10][cH:11]1)[c:20]1[cH:21][cH:22][c:23]([O:26][CH3:27])[cH:24][cH:25]1)=[O:28]

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 75646CyclopropanemethanamineHCID 210443143-(4-Chloro-2-phenylamino-pyrimidin-5-yl)-2-(4-methoxy-phenyl)-propionic acid methyl ester

Product 1

HCID 210443193-(2-Phenylamino-4-cyclopropylmethylamino-pyrimidin-5-yl)-2-(4-methoxy-phenyl)-propionic acid methyl ester

Sources & evidence

ORD record
ord-0d39cc1519114b048523e41481d99b18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

Loading…