Ammonium → (2-Amino-6-chloro-pyridin-3-yl)-(2-methoxy-phenyl)-methanone

Reaction equation

[CH2:28]1[O:29][CH2:30][CH2:31][O:32][CH2:33]1.[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[Cl:1][c:2]1[n:3][c:4]([Cl:18])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:16][CH3:17])[cH:12][cH:13][cH:14][cH:15]1.[NH4+:19].[OH-:20].[OH2:21]>>[c:2]1([NH2:19])[n:3][c:4]([Cl:18])[cH:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:16][CH3:17])[cH:12][cH:13][cH:14][cH:15]1

Participants

Reactant 6

HCID 223Ammonium

HCID 961Hydroxide

HCID 962Water

HCID 8857Ethyl Acetate

HCID 312751,4-Dioxane

HCID 59789365(2,6-Dichloro-pyridin-3-yl)-(2-methoxy-phenyl)-methanone

Product 1

HCID 58590832(2-Amino-6-chloro-pyridin-3-yl)-(2-methoxy-phenyl)-methanone

Sources & evidence

ORD record: ord-c22f7258afe7402aa50e61aeda471a61
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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