Water → Tert-butyl 8-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate

HRID 121692

Reaction equation

HRID 121692 reaction equation
[CH2:1]1[N:2]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:3][CH2:4][C:5]12[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2.[CH2:36]1[O:37][CH2:38][CH2:39][O:40][CH2:41]1.[CH3:30][CH2:31][O:32][C:33]([CH3:34])=[O:35].[Cl:18][c:19]1[n:20][c:21]([Cl:28])[c:22]2[c:23]([n:24]1)[cH:25][cH:26][o:27]2.[OH2:29]>>[CH2:1]1[N:2]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:3][CH2:4][C:5]12[CH2:6][CH2:7][N:8]([c:21]1[n:20][c:19]([Cl:18])[n:24][c:23]3[c:22]1[o:27][cH:26][cH:25]3)[CH2:9][CH2:10]2

Participants

6

Reactant 5

HCID 962WaterHCID 8857Ethyl AcetateHCID 312751,4-DioxaneHCID 34178604tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylateHCID 457899682,4-Dichlorofuro[3,2-D]pyrimidine

Product 1

HCID 86665112Tert-butyl 8-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-2-carboxylate

Sources & evidence

ORD record
ord-f0fddea1423a4251bbb7594af39f7a45
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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