Hydrochloric Acid → 4-chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-amine

Reaction equation

[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11])[nH:12][cH:13][c:14]2[N+:15]([O-:16])=[O:17].[ClH:20].[Na+:19].[OH-:18]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11])[nH:12][cH:13][c:14]2[NH2:15]

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 602053074-chloro-3-nitro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 602053084-chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-amine

Sources & evidence

ORD record: ord-aad466ef076948c280a3a816b3b5e036
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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