Chloride → 5-Chloro-2-(2,2-difluoroacetamido)benzenesulphonamide

HRID 121843

Reaction equation

HRID 121843 reaction equation
[Cl-:19].[F:20][CH:21]([C:22](=[O:23])[OH:24])[F:25].[NH2:1][c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH2:12])[cH:4][c:5]([Cl:8])[cH:6][cH:7]1.[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1.[cH:13]1[cH:14][cH:15][n:16][cH:17][cH:18]1>>[NH:1]([c:2]1[c:3]([S:9](=[O:10])(=[O:11])[NH2:12])[cH:4][c:5]([Cl:8])[cH:6][cH:7]1)[C:22]([CH:21]([F:20])[F:25])=[O:23]

Participants

6

Reactant 5

HCID 312ChlorideHCID 1049PyridineHCID 9788Difluoroacetic acidHCID 312751,4-DioxaneHCID 122955502-Amino-5-chlorobenzenesulphonamide

Product 1

HCID 231042325-Chloro-2-(2,2-difluoroacetamido)benzenesulphonamide

Sources & evidence

ORD record
ord-e97f4280d4bd4318acaa7b579a2794dc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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