Dimethyl Sulfoxide → 4-Cyclopropylmethoxy-4-(4-fluorophenyl)-1-phenylcyclohexanecarbonitrile
Reaction equation
[Br:25][CH2:26][CH:27]1[CH2:28][CH2:29]1.[CH3:31][S:32](=[O:33])[CH3:34].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([OH:22])[CH2:9][CH2:10][C:11]([C:14]#[N:15])([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1.[K+:24].[OH-:23].[OH2:30]>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([O:22][CH2:26][CH:27]3[CH2:28][CH2:29]3)[CH2:9][CH2:10][C:11]([C:14]#[N:15])([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-560f2a840c904600a2c78397b20929cd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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