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Tetrahydrofuran → N-[(2,2-Dimethoxy)ethyl]-N-(2-pyridyl)cyclohexanecarboxamide

HRID 1229299
Notes
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Reaction equation

HRID 1229299 reaction equation
[CH2:14]([Li:15])[CH2:16][CH2:17][CH3:18].[CH3:1][O:2][CH:3]([CH2:4][NH:5][c:6]1[n:7][cH:8][cH:9][cH:10][cH:11]1)[O:12][CH3:13].[CH:19]1([C:25](=[O:26])[Cl:27])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH3:1][O:2][CH:3]([CH2:4][N:5]([c:6]1[n:7][cH:8][cH:9][cH:10][cH:11]1)[C:25]([CH:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1)=[O:26])[O:12][CH3:13]
ParticipantsSources & evidenceReaction notes

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 75938Cyclohexanecarbonyl chlorideHCID 217139332-(2,2-Dimethoxyethylamino)pyridineHCID 178418339Butyllithium

Product 1

HCID 21713913N-[(2,2-Dimethoxy)ethyl]-N-(2-pyridyl)cyclohexanecarboxamide

Sources & evidence

ORD record
ord-ea689291ecbf472db2d854a8a8e05e5f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes