Potassium Cation → methyl 2-(9-bromo-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indol-2-yl)acetate

Reaction equation

[Br:15][CH2:16][C:17](=[O:18])[O:19][CH3:20].[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]1[CH:5]([CH2:4]2)[CH2:14][NH:13][CH2:12][CH2:11]1.[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][C:28]#[N:29].[K+:25].[K+:26]>>[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]1[CH:5]([CH2:4]2)[CH2:14][N:13]([CH2:16][C:17](=[O:18])[O:19][CH3:20])[CH2:12][CH2:11]1

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6342Acetonitrile

HCID 19660Carbonate Ion

HCID 60984Methyl bromoacetate

HCID 223380779-Bromo-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indole

Product 1

HCID 69414323methyl 2-(9-bromo-3,4,10,10a-tetrahydro-1H-pyrazino[1,2-a]indol-2-yl)acetate

Sources & evidence

ORD record: ord-b5b804027e5440cc8e7bd28adfd29a68
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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