Water → 6-[3-(2-Fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-N-(2,2,2-trifluoro-ethyl)-nicotinamide
Reaction equation
[CH3:11][O:12][C:13]([c:14]1[cH:15][n:16][c:17]([O:20][CH2:21][c:22]2[c:23](-[c:28]3[c:29]([F:34])[cH:30][cH:31][cH:32][cH:33]3)[n:24][o:25][c:26]2[CH3:27])[cH:18][cH:19]1)=[O:35].[CH3:1][Al:2]([CH3:3])[CH3:4].[F:5][C:6]([CH2:7][NH2:8])([F:9])[F:10].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[OH2:36]>>[F:5][C:6]([CH2:7][NH:8][C:13](=[O:12])[c:14]1[cH:15][n:16][c:17]([O:20][CH2:21][c:22]2[c:23](-[c:28]3[c:29]([F:34])[cH:30][cH:31][cH:32][cH:33]3)[n:24][o:25][c:26]2[CH3:27])[cH:18][cH:19]1)([F:9])[F:10]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d65427149658463aac9ce42841261904
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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