Hydrochloric Acid → 4-(2-Fluoro-5-methoxycarbonyloxy-4-methylanilino)-7-(3-morpholinopropionamido)quinazoline
Reaction equation
[CH2:1]1[CH2:2][CH2:3][CH:4]([N:5]=[C:6]=[N:7][CH:8]2[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:14][CH2:15]1.[ClH:27].[NH2:28][c:29]1[cH:30][cH:31][c:32]2[c:33]([NH:39][c:40]3[c:41]([F:52])[cH:42][c:43]([CH3:51])[c:44]([O:46][C:47](=[O:48])[O:49][CH3:50])[cH:45]3)[n:34][cH:35][n:36][c:37]2[cH:38]1.[O:16]1[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][C:24](=[O:25])[OH:26])[CH2:20][CH2:21]1.[cH:53]1[cH:54][cH:55][n:56][cH:57][cH:58]1>>[O:16]1[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][C:24](=[O:26])[NH:28][c:29]2[cH:30][cH:31][c:32]3[c:33]([NH:39][c:40]4[c:41]([F:52])[cH:42][c:43]([CH3:51])[c:44]([O:46][C:47](=[O:48])[O:49][CH3:50])[cH:45]4)[n:34][cH:35][n:36][c:37]3[cH:38]2)[CH2:20][CH2:21]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ae5bfe9f6e4d4e8a87145dcdddb8f8ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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